{"id":38,"date":"2021-03-06T18:57:16","date_gmt":"2021-03-06T17:57:16","guid":{"rendered":"http:\/\/www.congressi.unisi.it\/icameeting\/?page_id=38"},"modified":"2021-06-08T09:38:06","modified_gmt":"2021-06-08T07:38:06","slug":"programma","status":"publish","type":"page","link":"https:\/\/www.congressi.unisi.it\/icameeting\/programma\/","title":{"rendered":"Schedule"},"content":{"rendered":"\n

Monday, June 7th<\/sup> 2021<\/strong><\/p>\n\n\n\n

10:20<\/strong> Welcome by AIC-BMM Committee<\/strong><\/p>\n\n\n\n

10:30 Morning Session I<\/strong>
Protein small molecule interactions – Structure Based Drug design<\/em>
Chair: Cecilia Pozzi <\/strong>\u2013 Universit\u00e0 di Siena – IT<\/p>\n\n\n\n

Invited speaker:
Alice Douangamath<\/strong> – Diamond Light Source – UK
Addressing COVID-19 With Fragment- Based Drug Discovery<\/em>

11.00 <\/strong>Selected talks
Theo Battista<\/strong> – Sapienza Universit\u00e0 di Roma \u2013 IT
Anti-trypanosomatidal drug discovery: a challenge for structural biology<\/em>
Giovanni Bisello<\/strong> – Universit\u00e0 di Verona – IT
Human Aromatic L-Amino Acid Decarboxylase (AADC) in its native and inhibitor bound crystal structure solved at different pH values<\/em><\/p>\n\n\n\n

11.40<\/strong> Break<\/p>\n\n\n\n

11.50<\/strong> Selected talks
Marta Ferraroni<\/strong> \u2013 Universit\u00e0 di Firenze \u2013 IT
Structural insights into Schistosoma mansoni Carbonic Anhydrase Inhibition<\/em>
Francesca Paoletti<\/strong> – National Institute of Chemistry Ljubljana – SLO Endogenous    Modulators of Neurotrophin Signaling: Landscape of the Transient ATP- NGF Interactions<\/em>
Simona Fermani<\/strong> – Universit\u00e0 di Bologna – IT
Plant GADPH is primed to form globular insoluble aggregates by specific cysteine glutathionylation<\/em><\/p>\n\n\n\n

12:50<\/strong> Invited speaker Societ\u00e0 Italiana Luce di Sincrotrone (SILS)
Michele Cianci<\/strong> – Universit\u00e0 Politecnica delle Marche, Ancona \u2013 IT
The synergy between SILS and AIC-BMM: a personal perspective<\/em><\/p>\n\n\n\n

14:30<\/strong> Afternoon Session II<\/strong>
Macromolecular complexes – Protein-protein – Protein-nucleic<\/em> acid<\/em>
interactions<\/em>
Chair: Sebastiano Pasqualato <\/strong>– Istituto Europeo di Oncologia, Milano – IT<\/p>\n\n\n\n

Invited speaker
Filippo Mancia<\/strong> – Columbia University – USA
Structural basis of Wnt secretion by its carrier WLS<\/em><\/p>\n\n\n\n

15:00<\/strong>   Selected talks
Ludovica Lopresti<\/strong> – Universit\u00e0 di Siena – IT
Structural insight into YAP-TEAD4 protein- protein interactions as target for cancer treatment<\/em>
Cristina Renna<\/strong> – Istituto Europeo di Oncologia, Milano – IT
The protein NuMA acts as amitotic dynein\/dynactin adaptor<\/em>
Stefano Ricagno<\/strong> – Universit\u00e0 di Milano – IT
Structural bases of Light Chain Amyloidosis: the role of the native and the fibrillar states<\/em><\/p>\n\n\n\n

16.00<\/strong> Break<\/p>\n\n\n\n

16:10  <\/strong>Selected talks
Marta Semrau<\/strong> – Sincrotrone Elettra Trieste e Universit\u00e0 di Trento – IT
Structural  characterization of the PTG and PTG\/PP1 complex<\/em>
Vincenzo Taibi<\/strong> – Fondazione Istituto FIRC di Oncologia Molecolare – IT
Structural insight of polyubiquitin chain formation mediated by NEDD4 HECT ligase<\/em>
Sharon Spizzichino<\/strong> – Universit\u00e0 La Sapienza di Roma – IT
Structural clues of serine hydroxymethyltranferase (SHMT) riboregulation<\/em><\/p>\n\n\n\n

17:10<\/strong> Invited speaker Societ\u00e0 Italiana di Biofisica Pura e Applicata (SIBPA)
Francesco Spinozzi<\/strong> – Universit\u00e0 Politecnica delle Marche – IT
SIBPA and AIC-BMM: perspectives for collaborative research<\/em><\/p>\n\n\n\n

<\/p>\n\n\n\n

Tuesday, June 8th<\/sup> 2021<\/strong><\/p>\n\n\n\n

10:00<\/strong> Morning Session III<\/strong>
Structures of Membrane proteins or Large Macromolecular Complexe<\/em>s, CryoEM<\/em>
Chair: Linda Celeste Montemiglio<\/strong> – Istituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche, Roma – IT<\/p>\n\n\n\n

10:05<\/strong> Invited speaker
Stefan Kochanek<\/strong> – University of Ulm – DE
Interaction of Huntingtin and HAP40: what we know (little) and what we don\u2019t know (much)<\/em>

10:35<\/strong>\u00a0\u00a0 Selected talks
Pietro Roversi<\/strong> – Leicester Institute of Structural and Chemical Biology – UK and Consiglio Nazionale delle Ricerche Milano – IT
Towards the CryoEM structure of EDEM:PDI, the endoplasmic reticulum associated \u00a0degradation glycoprotein misfolding checkpoint<\/em>
Alessandro Grinzato<\/strong> – ESRF Grenoble – FR and Universit\u00e0 di Padova – IT
CryoEM structure of tetanus neurotoxin in complex with two monoclonal antibodies that interfere with toxin binding and translocation into neurons<\/em>
Francesco Margheriti<\/strong> – Scuola Normale Superiore di Pisa – IT
CryoEM analysis of membrane NAPE-PLD associated to nanodiscs<\/em>

11:35<\/strong> Break

11:45<\/strong> Invited speaker
Martino Bolognesi<\/strong> – Universit\u00e0 di Milano – IT
Mapping gating structural transitions and ion permeation in the HCN4 pacemaker channel<\/em>

12:15<\/strong>\u00a0Invited speaker
Giuseppe Zanotti<\/strong> -Universit\u00e0 di Padova -IT
Cryo-electron microscopy of Campylobacter jejuni serine protease HtrA<\/em>

14:30 – 15:45<\/strong> Round Table<\/strong>
New infrastructures for Italian structural biology research<\/em>
Chair: Andrea Ilari<\/strong> – Istituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche, Roma – IT

15:45 <\/strong> Afternoon Session IV<\/strong>
Computational Methods – Structural Bioinformatics<\/em>
Chair: Danilo Benny Belviso <\/strong>– Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Bari – IT <\/em>

15:50<\/strong> Invited speaker Societ\u00e0 Italiana di Bioinformatica (BITS)
Anna Marabotti<\/strong> \u2013 Universit\u00e0 di Salerno \u2013 IT
Prediction of protein structure: The ultimate solution lies Deep (in) Mind<\/em><\/p>\n\n\n\n

16:20<\/strong> Selected talks
Nicole Balasco<\/strong> – Institute of Biostructures and Bioimaging, Consiglio Nazionale delle Ricerche, Napoli \u2013 IT
Unraveling the determinants of the conformational preferences of amino acid residues: the role of the local geometry<\/em>
Gianluca Santoni<\/strong> – European Synchrotron Radiation Facility, Grenoble -FR
The coronavirus structural taskforce<\/em><\/p>\n\n\n\n

17:00<\/strong> Invited speaker
James Fraser<\/strong> – University of California, San Francisco – USA 
Targeting COVID-19 Viral Enzymes in an Evolving Landscape of Publishing and Peer Review<\/em><\/p>\n\n\n\n

Wednesday, June 9th<\/sup> 2021<\/strong><\/p>\n\n\n\n

10:00 Morning Session V<\/strong>
Cool & hot structures – Difficult Cases – Disordered Proteins<\/em>
Chair: Rocco Caliandro<\/strong> – Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Bari – IT<\/p>\n\n\n\n

10:05<\/strong> Invited speaker
Rita Berisio<\/strong> – Istituto di Biostrutture e Bioimmagini CNR – IT
Cell wall degrading enzymes against challenging antimicrobial resistant           infectious pathogens<\/em>

10:35<\/strong>   Selected talks
Danilo Benny Belviso<\/strong> – Istituto di Cristallografia, Consiglio Nazionale delle Ricerche Bari – IT
Structural characterization of C-terminal domain of NSD2 and NSD3 proteins by Small-Angle X-ray Scattering<\/em>
Gabriele Giachin<\/strong> – Universit\u00e0 di Padova \u2013 IT
Conformational selection mechanisms in human prion protein mutants bound to a therapeutic nanobody<\/em><\/p>\n\n\n\n

11:15<\/strong> Break

11:25<\/strong>   Invited speaker   
Roberta Pierattelli<\/strong> \u2013 Universit\u00e0 di Firenze \u2013 IT
Just flexible linkers?<\/em><\/p>\n\n\n\n

11:55<\/strong>   Selected talks
Sonia Covaceuszach <\/strong>– Institute of Crystallography, Consiglio Nazionale delle Ricerche, Trieste Outstation \u2013 IT
A combined evolutionary and structural approach to disclose the primary structural determinants essential for proneurotrophins biological functions<\/em>
Elisa Costanzi<\/strong> \u2013 Sincrotrone Elettra \u2013 TS
Elettra against COVID-19: Joint forces within \u201cExscalate4COV\u201d project<\/em><\/p>\n\n\n\n

12:35   <\/strong>Invited speaker
Annie Heroux <\/strong>– Sincrotrone Elettra – IT
Remote access at Elettra: XRD2 Beamline \u2013 MX home delivery<\/em><\/p>\n\n\n\n

13:00<\/strong> Prize for Best Young Crystallographer presentation andConcluding remarks by AIC-BMM Committee<\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/p>\n\n\n\n

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Monday, June 7th 2021 10:20 Welcome by AIC-BMM Committee 10:30 Morning Session IProtein small molecule interactions – Structure Based Drug designChair: Cecilia Pozzi \u2013 Universit\u00e0 di Siena – IT Invited speaker:Alice Douangamath – Diamond Light Source – UKAddressing COVID-19 With Fragment- Based Drug Discovery 11.00 Selected talksTheo Battista – Sapienza Universit\u00e0 di Roma \u2013 ITAnti-trypanosomatidal drug discovery: […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"saved_in_kubio":false,"footnotes":""},"class_list":["post-38","page","type-page","status-publish","hentry"],"kubio_ai_page_context":{"short_desc":"","purpose":"general"},"_links":{"self":[{"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/pages\/38","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/comments?post=38"}],"version-history":[{"count":37,"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/pages\/38\/revisions"}],"predecessor-version":[{"id":245,"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/pages\/38\/revisions\/245"}],"wp:attachment":[{"href":"https:\/\/www.congressi.unisi.it\/icameeting\/wp-json\/wp\/v2\/media?parent=38"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}