Sunday 21st May 2023
14.00 – 19.00 Registration and posters’ billsticking
Sala Bracci – Certosa di Pontignano – Maurizio Botta’s Friends afternoon
Opening Remarks: Greetings from the Magnificent Rector Prof. Roberto Di Pietra
17.00 Welcome Prof. Bruno Botta University of Roma “La Sapienza” (Italy)
17.15 Prof. Stephen Neidle University College London (UK)
A structure-based approach to the design of quadruplex DNA targeting anticancer drugs:
identification of a clinical candidate
17.40 Prof. Karl-Heinz Altmann ETH Zürich (Switzerland)
The Chemistry and Biology of (Certain) Macrocyclic Natural Products
18.10 Prof. Thierry Langer University of Wien (Austria)
Merging computational and medicinal chemistry: Maurizio Botta as a role model
18.30 Prof. Dieter Schinzer University of Magdeburg (Germany)
Total Synthesis of Biologically Active Natural Products
19.30 Dinner
21.00 Official Opening Prof. Elena Petricci
21.15 Dr. Rino Rappuoli Biotecnopolo (Italy)
Digital Vaccines
Monday 22nd May 2023
Sala Bracci – Certosa di Pontignano
Green Chemistry in Drug Synthesis
09.00 Dr. Tobias Ritter Max Planck Institut (Germany)
Late-Stage Functionalizations
09.45 Prof. Luigi Vaccaro University of Perugia (Italy)
Sustainability challenges and synthetic tools for target molecules
10.30 Prof. Kurt Faber University of Graz (Austria)
Biocatalytic API-Synthesis
11.15 Coffee break
11.45 Prof. Daniele Castagnolo University College London (UK)
Biocatalytic and chemo-enzymatic cascades in the synthesis of drug building blocks
12.30 Prof. Darren Dixon University of Oxford (UK)
New Broad Scope Strategies for Amine Synthesis
13.15 Dr. Alice Pedruzzi Büchi (Italy)
Chromatography with supercritical fluid applied to the preparatory purification technique
13.30 Lunch
14.30 Poster session
Symeres Afternoon
New Synthetic Strategies in Medical Chemistry
15.30 Dr. André De Vries Symeres (Netherlands)
Moving towards green chemistry in drug development, why and how
16.15 Symeres – AXXAM TEAM WORKS
17.15 Coffee break
17.45 Symeres – AXXAM TEAM WORKS
19.30 Dinner
21.00 AFTER DINNER: SYMERES Wine Tasting
Tuesday 23rd May 2023
Sala Bracci – Certosa di Pontignano
New Synthetic Strategies in Medicinal Chemistry
9.00 Dr. Anna K.H. Hirsch Helmholtz Centre for Infection Research (Germany)
Addressing under explored anti-infective drug targets
9.45 Prof. Maria Laura Bolognesi University of Bologna (Italy)
Sustainable synthesis of drugs and bioactive compounds from food waste
10.30 Dr. Lloyd Payne Arrepath (USA)
Harnessing microscopy with machine learning: the search for new classes of antibacterials’
11.15 Oral Communication 1
11.35 Coffee break
11.50 Dr. Maria Pia Catalani AXXAM (Italy)
Hit the road
12.20 Dr. Phil Cox AbbVie (USA)
Computational approaches to drug properties etc. His approach at Abbvie
13.00 Oral Communication 2
13.15 Flash Communication 1
13.22 Flash Communication 2
13.30 Lunch
14.30 Dr. Maria Rosaria Romano GSK (Italy)
New technologies pave the way for next generation glycoconjugate vaccines
15.00 Dr. Jacob Bush GSK (UK)
Expanding the liganded proteome with reactive fragments
15.30 Dr. Louise Walport Crick Institute (UK)
15.55 Oral Communication 3
16.10 Flash Communication 3
16.17 Flash Communication 4
16.25 Flash Communication 5
16.32 Flash Communication 6
16.40 Coffee break
16.55 Dr. Samuele Cazzamalli and Francesca Migliorini Philochem (Switzerland)
Drug Discovery with DNA-encoded Libraries (DEL)
20.30 Bus departure from Certosa di Pontignano to Piazza Gramsci (Siena)
20.30 Social Dinner in Siena
Wednesday 24th May 2023
Sala Bracci – Certosa di Pontignano
09.00 Oral Communication 4
09.15 Oral Communication 5
09.30 Oral Communication 6
09.45 Flash Communication 7
09.52 Flash Communication 8
09.59 Flash Communication 9
10.06 Flash Communication 10
10.13 Flash Communication 11
10.20 Flash Communication 12
10.27 Best poster and Best team works awards
10.50 Coffee break
11.20 Presentation of best posters and team works
12.10 Closing lecture Dr. Russel Thomas Symeres (Netherlands)
21st Century drug discovery, challenges and some solutions
12.50 Closing Remarks Prof. Elena Petricci
13.00 Lunch